![]() ![]() Women after labor:the serum concentration of vitamin D and Ca++ falls rapidly.ĥ. Newborn infants: who are absolutely breastfed require vitamin D supplements because mother milk does not contain significant levels of the vitamin. Older people (> 50 years) due to: The decrease of ability of skin to convert 7- dehydrocholesterol to pre-vitamin D3. PEOPLE AT GREATER RISK OF DEVELOPING VITAMIN D DEFICIENCY 1. Regulation of cell growth and development (particularly WBCs and epithelial cells). Integrated function with parathyroid hormonein stabilization of Ca++ level in blood. Essential for normal bone growth during childhood and for maintaining bone density and strength during adulthood (as it increases Ca++ absorption from foods + increases Ca++ deposition into the skeleton). A fall in blood Ca++ stimulate active vitamin D production stimulates Ca++ absorption from food + release of Ca++ from bones + renal excretion of Ca++.Ģ. Vitamin D regulates Ca++ levels in the blood and tissues.NB: A healthy liver and kidneys are essential for optimum vitamin D status.īiosynthesis and Activation of Vitamin D3 Stored in Liverĭaily Requirment = 10μg vitamin D = 400 IU vitamin D. ![]() When needed by the body, it is then activated by the kidney to 1, 25 - di hydroxy vitamin D3. After absorption from foods or production in the skin, vitamin D is stored as 25-hydroxy- vitamin D3 in the liver.However, vitamin D3 is the preferred form for humans as its bioavailability is twice that of vitamin D2. Vitamin D2 (ergocalciferol) is another form of vitamin D synthesized by certain fungi and is used in many supplements. Vitamin D3 (cholecalciferol) is synthesized from 7-dehydrocholesterol in sun-exposed skin and found naturally in animal products such as eggs, fish and liver. ![]() Vitamin D The term “Vitamin D” refers to a family of related compounds biosynthesized from cholesterol and ergosterol.
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